An essential role for IL-2 receptor in regulatory T cell function

Regulatory T (T(reg)) cells, expressing abundant amounts of the IL-2 receptor (IL-2R), are reliant on IL-2 produced by activated T cells. This feature implied a key role for a simple network based on IL-2 consumption by T(reg) cells in their suppressor function. However, congenital deficiency in IL-...

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Detalles Bibliográficos
Autores principales: Chinen, Takatoshi, Kannan, Arun K., Levine, Andrew G, Fan, Xiying, Klein, Ulf, Zheng, Ye, Gasteiger, Georg, Feng, Yongqiang, Fontenot, Jason D., Rudensky, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071159/
https://www.ncbi.nlm.nih.gov/pubmed/27595233
http://dx.doi.org/10.1038/ni.3540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071159/
https://www.ncbi.nlm.nih.gov/pubmed/27595233
http://dx.doi.org/10.1038/ni.3540

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