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An essential role for IL-2 receptor in regulatory T cell function

Regulatory T (T(reg)) cells, expressing abundant amounts of the IL-2 receptor (IL-2R), are reliant on IL-2 produced by activated T cells. This feature implied a key role for a simple network based on IL-2 consumption by T(reg) cells in their suppressor function. However, congenital deficiency in IL-...

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Detalles Bibliográficos
Autores principales:	Chinen, Takatoshi, Kannan, Arun K., Levine, Andrew G, Fan, Xiying, Klein, Ulf, Zheng, Ye, Gasteiger, Georg, Feng, Yongqiang, Fontenot, Jason D., Rudensky, Alexander Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071159/ https://www.ncbi.nlm.nih.gov/pubmed/27595233 http://dx.doi.org/10.1038/ni.3540

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