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Tamoxifen in the Mouse Brain: Implications for Fate-Mapping Studies Using the Tamoxifen-Inducible Cre-loxP System

The tamoxifen-inducible Cre-loxP system is widely used to overcome gene targeting pre-adult lethality, to modify a specific cell population at desired time-points, and to visualize and trace cells in fate-mapping studies. In this study we focused on tamoxifen degradation kinetics, because for all ge...

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Detalles Bibliográficos
Autores principales: Valny, Martin, Honsa, Pavel, Kirdajova, Denisa, Kamenik, Zdenek, Anderova, Miroslava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071318/
https://www.ncbi.nlm.nih.gov/pubmed/27812322
http://dx.doi.org/10.3389/fncel.2016.00243