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Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase

The Src Homology 2 (SH2) domain is a structurally conserved protein domain that typically binds to a phosphorylated tyrosine in a peptide motif from the target protein. The SH2 domain of C-terminal Src kinase (Csk) contains a single disulfide bond, which is unusual for most SH2 domains. Although the...

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Detalles Bibliográficos
Autores principales: Liu, Dongsheng, Cowburn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071372/
https://www.ncbi.nlm.nih.gov/pubmed/27819029
http://dx.doi.org/10.1007/s41048-016-0025-4