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Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo

Intrahost genetic diversity and replication error rates are intricately linked to RNA virus pathogenesis, with alterations in viral polymerase fidelity typically leading to attenuation during infections in vivo. We have previously shown that norovirus intrahost genetic diversity also influences vira...

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Detalles Bibliográficos
Autores principales: Arias, Armando, Thorne, Lucy, Ghurburrun, Elsa, Bailey, Dalan, Goodfellow, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071534/
https://www.ncbi.nlm.nih.gov/pubmed/27777985
http://dx.doi.org/10.1128/mSphere.00279-16