Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia

Transthyretin (TTR) is a protein whose function has been associated to binding and distribution of thyroid hormones in the body and brain. However, little is known regarding the downstream signaling pathways triggered by wild-type TTR in the CNS either in neuroprotection of cerebral ischemia or in p...

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Detalles Bibliográficos
Autores principales: Gomes, J R, Nogueira, RS, Vieira, M, Santos, SD, Ferraz-Nogueira, J P, Relvas, J B, Saraiva, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071567/
https://www.ncbi.nlm.nih.gov/pubmed/27518433
http://dx.doi.org/10.1038/cdd.2016.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071567/
https://www.ncbi.nlm.nih.gov/pubmed/27518433
http://dx.doi.org/10.1038/cdd.2016.64

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