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A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors
Eukaryotic elongation factor 2 kinase (eEF2K) inhibitors may aid in the development of new therapeutic agents to combat cancer. Purified human eEF2K was obtained from an Escherichia coli expression system and a luminescence-based high-throughput screening (HTS) assay was developed using MH-1 peptide...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071636/ https://www.ncbi.nlm.nih.gov/pubmed/27818922 http://dx.doi.org/10.1016/j.apsb.2016.04.002 |