In vivo continuous evolution of genes and pathways in yeast

Directed evolution remains a powerful, highly generalizable approach for improving the performance of biological systems. However, implementations in eukaryotes rely either on in vitro diversity generation or limited mutational capacities. Here we synthetically optimize the retrotransposon Ty1 to en...

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Detalles Bibliográficos
Autores principales: Crook, Nathan, Abatemarco, Joseph, Sun, Jie, Wagner, James M., Schmitz, Alexander, Alper, Hal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071640/
https://www.ncbi.nlm.nih.gov/pubmed/27748457
http://dx.doi.org/10.1038/ncomms13051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071640/
https://www.ncbi.nlm.nih.gov/pubmed/27748457
http://dx.doi.org/10.1038/ncomms13051

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