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Active and adaptive Legionella CRISPR‐Cas reveals a recurrent challenge to the pathogen

Clustered regularly interspaced short palindromic repeats with CRISPR‐associated gene (CRISPR‐Cas) systems are widely recognized as critical genome defense systems that protect microbes from external threats such as bacteriophage infection. Several isolates of the intracellular pathogen Legionella p...

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Detalles Bibliográficos
Autores principales: Rao, Chitong, Guyard, Cyril, Pelaz, Carmen, Wasserscheid, Jessica, Bondy‐Denomy, Joseph, Dewar, Ken, Ensminger, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071653/
https://www.ncbi.nlm.nih.gov/pubmed/26936325
http://dx.doi.org/10.1111/cmi.12586