A Structure‐Guided Switch in the Regioselectivity of a Tryptophan Halogenase

Flavin‐dependent halogenases are potentially useful biocatalysts for the regioselective halogenation of aromatic compounds. Haloaromatic compounds can be utilised in the synthesis and biosynthesis of pharmaceuticals and other valuable products. Here we report the first X‐ray crystal structure of a t...

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Detalles Bibliográficos
Autores principales: Shepherd, Sarah A., Menon, Binuraj R. K., Fisk, Heidi, Struck, Anna‐Winona, Levy, Colin, Leys, David, Micklefield, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071727/
https://www.ncbi.nlm.nih.gov/pubmed/26840773
http://dx.doi.org/10.1002/cbic.201600051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071727/
https://www.ncbi.nlm.nih.gov/pubmed/26840773
http://dx.doi.org/10.1002/cbic.201600051

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