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Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer

BACKGROUND: Intratumoral heterogeneity presents a major obstacle to the widespread implementation of precision medicine. The authors assessed the origin of intratumoral heterogeneity in nonseminomatous germ cell tumor of the testis (NSGCT) and identified distinct tumor subtypes and a potentially let...

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Detalles Bibliográficos
Autores principales: Tu, Shi‐Ming, Bilen, Mehmet Asim, Hess, Kenneth R., Broaddus, Russell R., Kopetz, Scott, Wei, Chongjuan, Pagliaro, Lance C., Karam, Jose A., Ward, John F., Wood, Christopher G., Rao, Priya, Tu, Zachary H., General, Rosale, Chen, Adrienne H., Nieto, Yago L., Yeung, Sai‐ching J., Lin, Sue‐Hwa, Logothetis, Christopher J., Pisters, Louis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071733/
https://www.ncbi.nlm.nih.gov/pubmed/27018785
http://dx.doi.org/10.1002/cncr.29996