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Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer
BACKGROUND: Intratumoral heterogeneity presents a major obstacle to the widespread implementation of precision medicine. The authors assessed the origin of intratumoral heterogeneity in nonseminomatous germ cell tumor of the testis (NSGCT) and identified distinct tumor subtypes and a potentially let...
Autores principales: | Tu, Shi‐Ming, Bilen, Mehmet Asim, Hess, Kenneth R., Broaddus, Russell R., Kopetz, Scott, Wei, Chongjuan, Pagliaro, Lance C., Karam, Jose A., Ward, John F., Wood, Christopher G., Rao, Priya, Tu, Zachary H., General, Rosale, Chen, Adrienne H., Nieto, Yago L., Yeung, Sai‐ching J., Lin, Sue‐Hwa, Logothetis, Christopher J., Pisters, Louis L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071733/ https://www.ncbi.nlm.nih.gov/pubmed/27018785 http://dx.doi.org/10.1002/cncr.29996 |
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