IL‐12 and IL‐4 activate a CD39‐dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells

Immune responses to protein antigens involve CD4(+) and CD8(+) T cells, which follow distinct programs of differentiation. Naïve CD8 T cells rapidly develop cytotoxic T‐cell (CTL) activity after T‐cell receptor stimulation, and we have previously shown that this is accompanied by suppressive activit...

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Detalles Bibliográficos
Autores principales: Noble, Alistair, Mehta, Hema, Lovell, Andrew, Papaioannou, Eleftheria, Fairbanks, Lynette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071739/
https://www.ncbi.nlm.nih.gov/pubmed/26990545
http://dx.doi.org/10.1002/eji.201545939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071739/
https://www.ncbi.nlm.nih.gov/pubmed/26990545
http://dx.doi.org/10.1002/eji.201545939

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