Engineering prokaryotic channels for control of mammalian tissue excitability

The ability to directly enhance electrical excitability of human cells is hampered by the lack of methods to efficiently overexpress large mammalian voltage-gated sodium channels (VGSC). Here we describe the use of small prokaryotic sodium channels (BacNa(v)) to create de novo excitable human tissue...

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Detalles Bibliográficos
Autores principales: Nguyen, Hung X., Kirkton, Robert D., Bursac, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071848/
https://www.ncbi.nlm.nih.gov/pubmed/27752065
http://dx.doi.org/10.1038/ncomms13132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071848/
https://www.ncbi.nlm.nih.gov/pubmed/27752065
http://dx.doi.org/10.1038/ncomms13132

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