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Application of Targeted Mass Spectrometry for the Quantification of Sirtuins in the Central Nervous System

Sirtuin proteins have a variety of intracellular targets, thereby regulating multiple biological pathways including neurodegeneration. However, relatively little is currently known about the role or expression of the 7 mammalian sirtuins in the central nervous system. Western blotting, PCR and ELISA...

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Detalles Bibliográficos
Autores principales: Jayasena, T., Poljak, A., Braidy, N., Zhong, L., Rowlands, B., Muenchhoff, J., Grant, R., Smythe, G., Teo, C., Raftery, M., Sachdev, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071856/
https://www.ncbi.nlm.nih.gov/pubmed/27762282
http://dx.doi.org/10.1038/srep35391