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Application of Targeted Mass Spectrometry for the Quantification of Sirtuins in the Central Nervous System
Sirtuin proteins have a variety of intracellular targets, thereby regulating multiple biological pathways including neurodegeneration. However, relatively little is currently known about the role or expression of the 7 mammalian sirtuins in the central nervous system. Western blotting, PCR and ELISA...
Autores principales: | Jayasena, T., Poljak, A., Braidy, N., Zhong, L., Rowlands, B., Muenchhoff, J., Grant, R., Smythe, G., Teo, C., Raftery, M., Sachdev, P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071856/ https://www.ncbi.nlm.nih.gov/pubmed/27762282 http://dx.doi.org/10.1038/srep35391 |
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