A unique peptide deformylase platform to rationally design and challenge novel active compounds

Peptide deformylase (PDF) is considered an excellent target to develop antibiotics. We have performed an extensive characterization of a new PDF from the pathogen Streptococcus agalactiae, showing properties similar to other known PDFs. S. agalactiae PDF could be used as PDF prototype as it allowed...

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Detalles Bibliográficos
Autores principales: Fieulaine, Sonia, Alves de Sousa, Rodolphe, Maigre, Laure, Hamiche, Karim, Alimi, Mickael, Bolla, Jean-Michel, Taleb, Abbass, Denis, Alexis, Pagès, Jean-Marie, Artaud, Isabelle, Meinnel, Thierry, Giglione, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071857/
https://www.ncbi.nlm.nih.gov/pubmed/27762275
http://dx.doi.org/10.1038/srep35429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071857/
https://www.ncbi.nlm.nih.gov/pubmed/27762275
http://dx.doi.org/10.1038/srep35429

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