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SparRec: An effective matrix completion framework of missing data imputation for GWAS

Genome-wide association studies present computational challenges for missing data imputation, while the advances of genotype technologies are generating datasets of large sample sizes with sample sets genotyped on multiple SNP chips. We present a new framework SparRec (Sparse Recovery) for imputatio...

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Detalles Bibliográficos
Autores principales: Jiang, Bo, Ma, Shiqian, Causey, Jason, Qiao, Linbo, Hardin, Matthew Price, Bitts, Ian, Johnson, Daniel, Zhang, Shuzhong, Huang, Xiuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071878/
https://www.ncbi.nlm.nih.gov/pubmed/27762341
http://dx.doi.org/10.1038/srep35534