Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes

The recent success in ribosome structure determination by cryoEM has opened the door to defining structural differences between ribosomes of pathogenic organisms and humans and to understand ribosome-targeting antibiotics. Here, by direct electron-counting cryoEM, we have determined the structures o...

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Detalles Bibliográficos
Autores principales: Zhang, Xing, Lai, Mason, Chang, Winston, Yu, Iris, Ding, Ke, Mrazek, Jan, Ng, Hwee L., Yang, Otto O., Maslov, Dmitri A., Zhou, Z. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071889/
https://www.ncbi.nlm.nih.gov/pubmed/27752045
http://dx.doi.org/10.1038/ncomms13223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071889/
https://www.ncbi.nlm.nih.gov/pubmed/27752045
http://dx.doi.org/10.1038/ncomms13223

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