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Complement-independent retinal pathology produced by intravitreal injection of neuromyelitis optica immunoglobulin G

BACKGROUND: Neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system, is often associated with retinal abnormalities including thinning of the retinal nerve fiber layer and microcystic changes. Here, we demonstrate that passive transfer of an anti-aquaporin-4 auto...

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Detalles Bibliográficos
Autores principales: Felix, Christian M., Levin, Marc H., Verkman, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072328/
https://www.ncbi.nlm.nih.gov/pubmed/27765056
http://dx.doi.org/10.1186/s12974-016-0746-9