Synthesis and Biological Evaluation of a New Nitroimidazole-(99m)Tc-Complex for Imaging of Hypoxia in Mice Model

BACKGROUND: This study was specifically designed to develop a new (99m)Tc compound with 3-amino-4-[2-(2-methyl-5-nitro-1H-imidazol)-ethylamino]-4-oxo-butyrate (5-ntm-asp) and to verify whether this compound is feasible to be a radiopharmaceutical for hypoxic tumors. MATERIAL/METHODS: Metronidazole d...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Guan, Yanxing, Liu, Shaozheng, Chen, Qingjie, Li, Xiangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072380/
https://www.ncbi.nlm.nih.gov/pubmed/27752036
http://dx.doi.org/10.12659/MSM.898659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072380/
https://www.ncbi.nlm.nih.gov/pubmed/27752036
http://dx.doi.org/10.12659/MSM.898659

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