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Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer

Tumour cells have long been considered defective in mitochondrial respiration and mostly dependent on glycolytic metabolism. However, this assumption is currently challenged by several lines of evidence in a growing number of tumours. Ovarian cancer (OC) is one of the most lethal cancers worldwide,...

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Detalles Bibliográficos
Autores principales: Matassa, D S, Amoroso, M R, Lu, H, Avolio, R, Arzeni, D, Procaccini, C, Faicchia, D, Maddalena, F, Simeon, V, Agliarulo, I, Zanini, E, Mazzoccoli, C, Recchi, C, Stronach, E, Marone, G, Gabra, H, Matarese, G, Landriscina, M, Esposito, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072430/
https://www.ncbi.nlm.nih.gov/pubmed/27206315
http://dx.doi.org/10.1038/cdd.2016.39