Cargando…
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
Tumour cells have long been considered defective in mitochondrial respiration and mostly dependent on glycolytic metabolism. However, this assumption is currently challenged by several lines of evidence in a growing number of tumours. Ovarian cancer (OC) is one of the most lethal cancers worldwide,...
Autores principales: | Matassa, D S, Amoroso, M R, Lu, H, Avolio, R, Arzeni, D, Procaccini, C, Faicchia, D, Maddalena, F, Simeon, V, Agliarulo, I, Zanini, E, Mazzoccoli, C, Recchi, C, Stronach, E, Marone, G, Gabra, H, Matarese, G, Landriscina, M, Esposito, F |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072430/ https://www.ncbi.nlm.nih.gov/pubmed/27206315 http://dx.doi.org/10.1038/cdd.2016.39 |
Ejemplares similares
-
TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial–mesenchymal transition
por: Amoroso, Maria R, et al.
Publicado: (2016) -
TRAP1 Regulation of Cancer Metabolism: Dual Role as Oncogene or Tumor Suppressor
por: Matassa, Danilo Swann, et al.
Publicado: (2018) -
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1
por: Matassa, D S, et al.
Publicado: (2013) -
Regulation of mitochondrial complex III activity and assembly by TRAP1 in cancer cells
por: Matassa, Danilo Swann, et al.
Publicado: (2022) -
Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer
por: Criscuolo, Daniela, et al.
Publicado: (2020)