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Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs

The tumor suppressor protein promyelocytic leukemia (PML) is a key regulator of inflammatory responses and tumorigenesis and functions through the assembly of subnuclear structures known as PML nuclear bodies (NBs). The inflammation-related cytokine tumor necrosis factor-α (TNFα) is known to induce...

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Detalles Bibliográficos
Autores principales: Hsu, K-S, Guan, B-J, Cheng, X, Guan, D, Lam, M, Hatzoglou, M, Kao, H-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072441/
https://www.ncbi.nlm.nih.gov/pubmed/26383972
http://dx.doi.org/10.1038/cdd.2015.114