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Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation

The tumor-suppressor p53 is a transcription factor that prevents cancer development and is involved in regulation of various physiological processes. This is mediated both by induction of cell cycle arrest and apoptosis and by controlling the expression of a plethora of target genes, including secre...

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Detalles Bibliográficos
Autores principales: Charni, M, Molchadsky, A, Goldstein, I, Solomon, H, Tal, P, Goldfinger, N, Yang, P, Porat, Z, Lozano, G, Rotter, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072444/
https://www.ncbi.nlm.nih.gov/pubmed/26358154
http://dx.doi.org/10.1038/cdd.2015.119