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Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation
The tumor-suppressor p53 is a transcription factor that prevents cancer development and is involved in regulation of various physiological processes. This is mediated both by induction of cell cycle arrest and apoptosis and by controlling the expression of a plethora of target genes, including secre...
Autores principales: | Charni, M, Molchadsky, A, Goldstein, I, Solomon, H, Tal, P, Goldfinger, N, Yang, P, Porat, Z, Lozano, G, Rotter, V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072444/ https://www.ncbi.nlm.nih.gov/pubmed/26358154 http://dx.doi.org/10.1038/cdd.2015.119 |
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