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MicroRNA-125b regulates microglia activation and motor neuron death in ALS

Understanding the means by which microglia self-regulate the neuroinflammatory response helps modulating their reaction during neurodegeneration. In amyotrophic lateral sclerosis (ALS), classical NF-κB pathway is related to persistent microglia activation and motor neuron injury; however, mechanisms...

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Detalles Bibliográficos
Autores principales: Parisi, C, Napoli, G, Amadio, S, Spalloni, A, Apolloni, S, Longone, P, Volonté, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072447/
https://www.ncbi.nlm.nih.gov/pubmed/26794445
http://dx.doi.org/10.1038/cdd.2015.153