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Mapping the genomic diversity of HCV subtypes 1a and 1b: Implications of structural and immunological constraints for vaccine and drug development

Despite significant progress in hepatitis C (HCV) treatment, global viral eradication remains a challenge. An in-depth map of its genome diversity within the context of structural and immunological constraints could contribute to the design of pan-genotypic antivirals and preventive vaccines. For su...

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Detalles Bibliográficos
Autores principales: Cuypers, Lize, Li, Guangdi, Neumann-Haefelin, Christoph, Piampongsant, Supinya, Libin, Pieter, Van Laethem, Kristel, Vandamme, Anne-Mieke, Theys, Kristof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072459/
https://www.ncbi.nlm.nih.gov/pubmed/27774307
http://dx.doi.org/10.1093/ve/vew024