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Multiple Evolutionary Origins of Ubiquitous Cu(2+) and Zn(2+) Binding in the S100 Protein Family
The S100 proteins are a large family of signaling proteins that play critical roles in biology and disease. Many S100 proteins bind Zn(2+), Cu(2+), and/or Mn(2+) as part of their biological functions; however, the evolutionary origins of binding remain obscure. One key question is whether divalent t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072561/ https://www.ncbi.nlm.nih.gov/pubmed/27764152 http://dx.doi.org/10.1371/journal.pone.0164740 |