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Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses

IFI16 (gamma-interferon-inducible protein 16), a predominantly nuclear protein involved in transcriptional regulation, also functions as an innate immune response DNA sensor and induces the IL-1β and antiviral type-1 interferon-β (IFN-β) cytokines. We have shown that IFI16, in association with BRCA1...

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Detalles Bibliográficos
Autores principales: Iqbal, Jawed, Ansari, Mairaj Ahmed, Kumar, Binod, Dutta, Dipanjan, Roy, Arunava, Chikoti, Leela, Pisano, Gina, Dutta, Sujoy, Vahedi, Shahrooz, Veettil, Mohanan Valiya, Chandran, Bala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072618/
https://www.ncbi.nlm.nih.gov/pubmed/27764250
http://dx.doi.org/10.1371/journal.ppat.1005967