Cargando…
Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses
IFI16 (gamma-interferon-inducible protein 16), a predominantly nuclear protein involved in transcriptional regulation, also functions as an innate immune response DNA sensor and induces the IL-1β and antiviral type-1 interferon-β (IFN-β) cytokines. We have shown that IFI16, in association with BRCA1...
Autores principales: | Iqbal, Jawed, Ansari, Mairaj Ahmed, Kumar, Binod, Dutta, Dipanjan, Roy, Arunava, Chikoti, Leela, Pisano, Gina, Dutta, Sujoy, Vahedi, Shahrooz, Veettil, Mohanan Valiya, Chandran, Bala |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072618/ https://www.ncbi.nlm.nih.gov/pubmed/27764250 http://dx.doi.org/10.1371/journal.ppat.1005967 |
Ejemplares similares
-
Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses
por: Ansari, Mairaj Ahmed, et al.
Publicado: (2015) -
BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses
por: Dutta, Dipanjan, et al.
Publicado: (2015) -
ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi’s Sarcoma-Associated Herpesvirus
por: Kumar, Binod, et al.
Publicado: (2016) -
Interferon-γ-inducible protein 16 (IFI16) is required for the maintenance of Epstein-Barr virus latency
por: Pisano, Gina, et al.
Publicado: (2017) -
EphrinA2 Regulates Clathrin Mediated KSHV Endocytosis in Fibroblast Cells by Coordinating Integrin-Associated Signaling and c-Cbl Directed Polyubiquitination
por: Dutta, Dipanjan, et al.
Publicado: (2013)