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The CORM ALF-186 Mediates Anti-Apoptotic Signaling via an Activation of the p38 MAPK after Ischemia and Reperfusion Injury in Retinal Ganglion Cells

PURPOSE: Ischemia and reperfusion injury may induce apoptosis and lead to sustained tissue damage and loss of function, especially in neuronal organs. While carbon monoxide is known to exert protective effects after various harmful events, the mechanism of carbon monoxide releasing molecules in neur...

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Detalles Bibliográficos
Autores principales: Ulbrich, Felix, Kaufmann, Kai B., Meske, Alexander, Lagrèze, Wolf A., Augustynik, Michael, Buerkle, Hartmut, Ramao, Carlos C., Biermann, Julia, Goebel, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072679/
https://www.ncbi.nlm.nih.gov/pubmed/27764224
http://dx.doi.org/10.1371/journal.pone.0165182