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Step-Wise Increase in Tigecycline Resistance in Klebsiella pneumoniae Associated with Mutations in ramR, lon and rpsJ

Klebsiella pneumoniae is a gram-negative bacterium that causes numerous diseases, including pneumonia and urinary tract infections. An increase in multidrug resistance has complicated the treatment of these bacterial infections, and although tigecycline shows activity against a broad spectrum of bac...

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Detalles Bibliográficos
Autores principales: Fang, Li, Chen, Qiong, Shi, Keren, Li, Xi, Shi, Qiucheng, He, Fang, Zhou, Jiancang, Yu, Yunsong, Hua, Xiaoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072711/
https://www.ncbi.nlm.nih.gov/pubmed/27764207
http://dx.doi.org/10.1371/journal.pone.0165019