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Is Endotoxemia in Stable Hemodialysis Patients an Artefact? Limitations of the Limulus Amebocyte Lysate Assay and Role of (1→3)-β-D Glucan

BACKGROUND: Elevated blood endotoxin levels are frequently reported in the dialysis population and are strongly linked with inflammation, a major predictor of mortality. Virtually all studies have employed the Limulus Amoebocyte Lysate (LAL) assay to detect endotoxin. However this assay is not endot...

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Detalles Bibliográficos
Autores principales: Wong, Jonathan, Zhang, Yonglong, Patidar, Ashish, Vilar, Enric, Finkelman, Malcolm, Farrington, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072723/
https://www.ncbi.nlm.nih.gov/pubmed/27764208
http://dx.doi.org/10.1371/journal.pone.0164978