A Novel Diphenylthiosemicarbazide Is a Potential Insulin Secretagogue for Anti-Diabetic Agent

Insulin secretagogues are used for treatment of type 2 diabetes. We attempted to discover novel small molecules to stimulate insulin secretion by using in silico similarity search using sulfonylureas as query, followed by measurement of insulin secretion. Among 38 compounds selected by in silico sim...

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Detalles Bibliográficos
Autores principales: Sugawara, Kenji, Honda, Kohei, Reien, Yoshie, Yokoi, Norihide, Seki, Chihiro, Takahashi, Harumi, Minami, Kohtaro, Mori, Ichiro, Matsumoto, Akio, Nakaya, Haruaki, Seino, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072725/
https://www.ncbi.nlm.nih.gov/pubmed/27764176
http://dx.doi.org/10.1371/journal.pone.0164785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072725/
https://www.ncbi.nlm.nih.gov/pubmed/27764176
http://dx.doi.org/10.1371/journal.pone.0164785

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