Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability

In the current work, a rapid, specific, sensitive and validated liquid chromatography tandem mass-spectrometric method was developed for the quantification of ponatinib (PNT) in human plasma and rat liver microsomes (RLMs) with its application to metabolic stability. Chromatographic separation of PN...

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Detalles Bibliográficos
Autores principales: Kadi, Adnan A., Darwish, Hany W., Attwa, Mohamed W., Amer, Sawsan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072736/
https://www.ncbi.nlm.nih.gov/pubmed/27764191
http://dx.doi.org/10.1371/journal.pone.0164967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072736/
https://www.ncbi.nlm.nih.gov/pubmed/27764191
http://dx.doi.org/10.1371/journal.pone.0164967

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