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Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability
In the current work, a rapid, specific, sensitive and validated liquid chromatography tandem mass-spectrometric method was developed for the quantification of ponatinib (PNT) in human plasma and rat liver microsomes (RLMs) with its application to metabolic stability. Chromatographic separation of PN...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072736/ https://www.ncbi.nlm.nih.gov/pubmed/27764191 http://dx.doi.org/10.1371/journal.pone.0164967 |