Heterologous Expression and Delivery of Biologically Active Exendin-4 by Lactobacillus paracasei L14

Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, is an excellent therapeutic peptide drug for type 2 diabetes due to longer lasting biological activity compared to GLP-1. This study explored the feasibility of using probiotic Lactobacillus paracasei as an oral vector for recombinant ex...

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Detalles Bibliográficos
Autores principales: Zeng, Zhu, Yu, Rui, Zuo, Fanglei, Zhang, Bo, Peng, Deju, Ma, Huiqin, Chen, Shangwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072737/
https://www.ncbi.nlm.nih.gov/pubmed/27764251
http://dx.doi.org/10.1371/journal.pone.0165130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072737/
https://www.ncbi.nlm.nih.gov/pubmed/27764251
http://dx.doi.org/10.1371/journal.pone.0165130

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