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Novel Nuclear Factor-KappaB Targeting Peptide Suppresses β-Amyloid Induced Inflammatory and Apoptotic Responses in Neuronal Cells

In the central nervous system (CNS), activation of the transcription factor nuclear factor-kappa B (NF-κβ) is associated with both neuronal survival and increased vulnerability to apoptosis. The mechanisms underlying these dichotomous effects are attributed to the composition of NF-κΒ dimers. In Alz...

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Detalles Bibliográficos
Autores principales: Srinivasan, Mythily, Bayon, Baindu, Chopra, Nipun, Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072831/
https://www.ncbi.nlm.nih.gov/pubmed/27764084
http://dx.doi.org/10.1371/journal.pone.0160314