HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24

Loss of HOXA5 expression occurs frequently in breast cancer and correlates with higher pathological grade and poorer disease outcome. However, how HOX proteins drive differentiation in mammalian cells is poorly understood. In this paper, we investigated cellular and molecular consequences of loss of...

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Detalles Bibliográficos
Autores principales: Teo, Wei Wen, Merino, Vanessa F., Cho, Soonweng, Korangath, Preethi, Liang, Xiaohui, Wu, Ren-chin, Neumann, Neil M., Ewald, Andrew J., Sukumar, Saraswati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073039/
https://www.ncbi.nlm.nih.gov/pubmed/27157614
http://dx.doi.org/10.1038/onc.2016.95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073039/
https://www.ncbi.nlm.nih.gov/pubmed/27157614
http://dx.doi.org/10.1038/onc.2016.95

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