Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

AIM: Maintenance of the blood and extracellular volume requires tight control of endothelial macromolecule permeability, which is regulated by cAMP signalling. This study probes the role of the cAMP mediators rap guanine nucleotide exchange factor 3 and 4 (Epac1 and Epac2) for in vivo control of mic...

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Detalles Bibliográficos
Autores principales: Kopperud, R. K., Rygh, C. Brekke, Karlsen, T. V., Krakstad, C., Kleppe, R., Hoivik, E. A., Bakke, M., Tenstad, O., Selheim, F., Lidén, Å., Madsen, L., Pavlin, T., Taxt, T., Kristiansen, K., Curry, F.‐R. E., Reed, R. K., Døskeland, S. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Cardiovascular Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073050/
https://www.ncbi.nlm.nih.gov/pubmed/27096875
http://dx.doi.org/10.1111/apha.12697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073050/
https://www.ncbi.nlm.nih.gov/pubmed/27096875
http://dx.doi.org/10.1111/apha.12697

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