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Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease
Alzheimer’s disease (AD) represents one of the most dramatic threats to healthy aging and devising effective treatments for this devastating condition remains a major challenge in biomedical research. Much has been learned about the molecular concepts that govern proteolytic processing of the amyloi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073117/ https://www.ncbi.nlm.nih.gov/pubmed/27638701 http://dx.doi.org/10.1007/s00401-016-1615-4 |