Cargando…
Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease
Alzheimer’s disease (AD) represents one of the most dramatic threats to healthy aging and devising effective treatments for this devastating condition remains a major challenge in biomedical research. Much has been learned about the molecular concepts that govern proteolytic processing of the amyloi...
Autores principales: | Andersen, Olav M., Rudolph, Ina-Maria, Willnow, Thomas E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073117/ https://www.ncbi.nlm.nih.gov/pubmed/27638701 http://dx.doi.org/10.1007/s00401-016-1615-4 |
Ejemplares similares
-
A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency
por: Andersen, Olav M., et al.
Publicado: (2022) -
Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain
por: Grear, Karrie E, et al.
Publicado: (2009) -
SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians
por: Miyashita, Akinori, et al.
Publicado: (2013) -
SORL1 Polymorphisms in Mexican Patients with Alzheimer’s Disease
por: Toral-Rios, Danira, et al.
Publicado: (2022) -
The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons
por: Mishra, Swati, et al.
Publicado: (2022)