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Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP

For proper mammalian brain development and functioning, the translation of many neuronal mRNAs needs to be repressed without neuronal activity stimulations. We have discovered that the expression of a subclass of neuronal proteins essential for neurodevelopment and neuron plasticity is co-regulated...

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Detalles Bibliográficos
Autores principales: Majumder, Pritha, Chu, Jen-Fei, Chatterjee, Biswanath, Swamy, Krishna B. S., Shen, Che-Kun James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073124/
https://www.ncbi.nlm.nih.gov/pubmed/27518042
http://dx.doi.org/10.1007/s00401-016-1603-8