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Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP
For proper mammalian brain development and functioning, the translation of many neuronal mRNAs needs to be repressed without neuronal activity stimulations. We have discovered that the expression of a subclass of neuronal proteins essential for neurodevelopment and neuron plasticity is co-regulated...
Autores principales: | Majumder, Pritha, Chu, Jen-Fei, Chatterjee, Biswanath, Swamy, Krishna B. S., Shen, Che-Kun James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073124/ https://www.ncbi.nlm.nih.gov/pubmed/27518042 http://dx.doi.org/10.1007/s00401-016-1603-8 |
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