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Pharmacodynamics and Pharmacokinetics Following Once-Daily and Twice-Daily Dosing of Tiotropium Respimat(®) in Asthma Using Standardized Sample-Contamination Avoidance

Background: This study was conducted to confirm the 24-hour bronchodilator efficacy and pharmacokinetic profile of once-daily tiotropium Respimat(®) 5 μg add-on to inhaled corticosteroids (ICS) in adults with symptomatic asthma. It used a trial protocol designed to minimize the risk of pharmacokinet...

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Detalles Bibliográficos
Autores principales: Beeh, Kai-Michael, Kirsten, Anne-Marie, Dusser, Daniel, Sharma, Ashish, Cornelissen, Piet, Sigmund, Ralf, Moroni-Zentgraf, Petra, Dahl, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073218/
https://www.ncbi.nlm.nih.gov/pubmed/26859538
http://dx.doi.org/10.1089/jamp.2015.1260