Novel Natural Product-like Caged Xanthones Bearing a Carbamate Moiety Exhibit Antitumor Potency and Anti-Angiogenesis Activity In vivo

DDO-6101, a simplified structure obtained from the Garcinia natural product (NP) gambogic acid (GA), has been previously shown to possess high cytotoxicity to a variety of human tumour cell lines. To improve its physicochemical properties and in vivo cytotoxic potency, a series of novel carbamate-be...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoli, Wu, Yue, Hu, Mingyang, Li, Xiang, Bao, Qichao, Bian, Jinlei, You, Qidong, Zhang, Xiaojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073322/
https://www.ncbi.nlm.nih.gov/pubmed/27767192
http://dx.doi.org/10.1038/srep35771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073322/
https://www.ncbi.nlm.nih.gov/pubmed/27767192
http://dx.doi.org/10.1038/srep35771

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