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Angiopoietin-2 attenuates angiotensin II-induced aortic aneurysm and atherosclerosis in apolipoprotein E-deficient mice

Angiogenesis and inflammation are implicated in aortic aneurysm and atherosclerosis and regulated by angiopoietin-2 (Angpt2). The effect of Angpt2 administration on experimental aortic aneurysm and atherosclerosis was examined. Six-month-old male apolipoprotein E deficient (ApoE(−/−)) mice were infu...

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Detalles Bibliográficos
Autores principales: Yu, Hongyou, Moran, Corey S., Trollope, Alexandra F., Woodward, Lynn, Kinobe, Robert, Rush, Catherine M., Golledge, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073347/
https://www.ncbi.nlm.nih.gov/pubmed/27767064
http://dx.doi.org/10.1038/srep35190