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Kinesin-5 Contributes to Spindle-length Scaling in the Evolution of Cancer toward Metastasis

During natural evolution, the spindles often scale with cell sizes to orchestrate accurate chromosome segregation. Whether in cancer evolution, when the constraints on genome integrity are relaxed, cancer cells may evolve the spindle to confer other advantages has not been investigated. Using invasi...

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Detalles Bibliográficos
Autores principales: Yang, Ching-Feng, Tsai, Wan-Yu, Chen, Wei-An, Liang, Kai-Wen, Pan, Cheng-Ju, Lai, Pei-Lun, Yang, Pan-Chyr, Huang, Hsiao-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073351/
https://www.ncbi.nlm.nih.gov/pubmed/27767194
http://dx.doi.org/10.1038/srep35767