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Kinesin-5 Contributes to Spindle-length Scaling in the Evolution of Cancer toward Metastasis
During natural evolution, the spindles often scale with cell sizes to orchestrate accurate chromosome segregation. Whether in cancer evolution, when the constraints on genome integrity are relaxed, cancer cells may evolve the spindle to confer other advantages has not been investigated. Using invasi...
Autores principales: | Yang, Ching-Feng, Tsai, Wan-Yu, Chen, Wei-An, Liang, Kai-Wen, Pan, Cheng-Ju, Lai, Pei-Lun, Yang, Pan-Chyr, Huang, Hsiao-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073351/ https://www.ncbi.nlm.nih.gov/pubmed/27767194 http://dx.doi.org/10.1038/srep35767 |
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